Summary for peptidase S12.001: D-Ala-D-Ala carboxypeptidase B

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors Pharma

 

Names
MEROPS NameD-Ala-D-Ala carboxypeptidase B
Other namesdac DD-peptidase (Streptomyces strain R61)
Domain architecture
MEROPS Classification
Classification Clan SE >> Subclan (none) >> Family S12 >> Subfamily (none) >> S12.001
HolotypeD-Ala-D-Ala carboxypeptidase B (Streptomyces lividans), Uniprot accession P15555 (peptidase unit: 32-380), MERNUM MER0000459
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Activity
Catalytic typeSerine
PeplistIncluded in the Peplist with identifier PL00379
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.16 (Serine-type carboxypeptidases) >> Peptidase 3.4.16.4
EnzymologyBRENDA database
PhysiologyActs in synthesis and remodelling of bacterial cell walls.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/-Scissile bond-/-/-/- (based on 11 cleavages)
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Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 1 0 1 1 0 0 0
Pro 0 0 0 0 0 0 0 0
Ala 0 0 0 0 0 0 0 0
Val 0 0 0 0 0 0 0 0
Leu 0 0 0 0 0 0 0 0
Ile 0 0 0 0 0 0 0 0
Met 0 0 0 0 0 0 0 0
Phe 0 0 0 0 0 0 0 0
Tyr 0 0 0 0 0 0 0 0
Trp 0 0 0 0 0 0 0 0
Ser 0 0 0 0 0 0 0 0
Thr 0 0 0 0 0 0 0 0
Cys 0 0 0 0 0 0 0 0
Asn 0 0 0 0 0 0 0 0
Gln 0 0 0 0 0 0 0 0
Asp 0 0 0 0 0 0 0 0
Glu 0 0 0 0 0 0 0 0
Lys 0 0 1 0 0 0 0 0
Arg 0 0 0 0 0 0 0 0
His 0 0 0 0 0 0 0 0