Summary for peptidase S21.006: herpesvirus 8-type assemblin

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors


MEROPS Nameherpesvirus 8-type assemblin
Other namesKaposi sarcoma virus assemblin, Kaposi sarcoma-associated herpesvirus peptidase
Domain architecture
MEROPS Classification
Classification Clan SH >> Subclan (none) >> Family S21 >> Subfamily (none) >> S21.006
Holotypeherpesvirus 8-type assemblin (human herpesvirus 8), Uniprot accession Q2HRB6 (peptidase unit: 10-249), MERNUM MER0004189
History Identifier created: MEROPS 3.03 (10 September 1998)
Catalytic typeSerine
PeplistIncluded in the Peplist with identifier PL00388
NC-IUBMBNot yet included in IUBMB recommendations.
PhysiologyPlays essential role in assembly of herpes virions by digesting scaffold protein.
Pharmaceutical relevancePotential target for antiviral drug (Marnett et al., 2004). .