Summary for peptidase S41.002: C-terminal processing peptidase-2

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Human EST Mouse EST Substrates Inhibitors

 

Names
MEROPS NameC-terminal processing peptidase-2
Other namesC-terminal processing protease-2, ctpA g.p. (higher plant), CtpA g.p. (Synechocystis sp.), photosystem II D1 protein-processing proteinase, tail-specific protease-2
Domain architecture
MEROPS Classification
Classification Clan SK >> Subclan (none) >> Family S41 >> Subfamily A >> S41.002
HolotypeC-terminal processing peptidase-2 (Scenedesmus obliquus), Uniprot accession O04073 (peptidase unit: 274-443), MERNUM MER0003413
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Activity
Catalytic typeSerine
PeplistIncluded in the Peplist with identifier PL00403
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.21 (Serine endopeptidases) >> Peptidase 3.4.21.102
EnzymologyBRENDA database
Proteolytic eventsCutDB database (2 cleavages)
PhysiologyCleaves an 8-16 residue peptide from the C-terminus of the D1 protein of the photosystem complex, a process that is essential for the assembly of the tetranuclear manganese cluster that functions as the site of photosynthetic oxidation of water, the source of electrons for the biosynthesis of organic compounds in the chloroplast (Anbudurai et al., 1994; Taguchi et al., 1995).