Summary for peptidase S53.001: sedolisin

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors

 

Names
MEROPS Namesedolisin
Other namesPseudomonas sp. pepstatin-insensitive carboxyl proteinase, Pseudomonas serine-carboxyl proteinase, pseudomonapepsin
Domain architecture
MEROPS Classification
Classification Clan SB >> Subclan (none) >> Family S53 >> Subfamily (none) >> S53.001
Holotypesedolisin (Pseudomonas sp. 101), Uniprot accession P42790 (peptidase unit: 216-585), MERNUM MER0000995
History Identifier created: MEROPS 5.3 (4 December 2000)
Activity
Catalytic typeSerine
PeplistIncluded in the Peplist with identifier PL00408
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.21 (Serine endopeptidases) >> Peptidase 3.4.21.100
EnzymologyBRENDA database
Proteolytic eventsCutDB database (1 cleavage)
PhysiologyBacterial nutrition.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage patternP/A/K/FScissile bond-/R/L/- (based on 22 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 1 0 0 0 0 0 0
Pro 13 0 0 0 0 0 2 0
Ala 1 15 1 0 1 0 0 0
Val 1 1 2 0 0 0 1 0
Leu 1 1 2 1 0 2 18 1
Ile 0 1 0 0 1 0 0 0
Met 0 0 0 0 0 0 0 0
Phe 0 0 1 18 0 0 0 1
Tyr 0 0 0 2 2 0 1 0
Trp 0 0 0 0 0 0 0 0
Ser 1 0 1 0 0 0 0 0
Thr 0 0 0 0 0 1 0 0
Cys 0 0 0 0 0 0 0 0
Asn 0 1 0 0 0 0 0 0
Gln 0 0 1 0 0 0 0 0
Asp 2 0 1 0 0 1 0 0
Glu 0 1 1 1 0 0 0 0
Lys 0 0 12 0 0 0 0 1
Arg 2 1 0 0 0 17 0 0
His 1 0 0 0 0 1 0 0