Summary for peptidase S53.005: kumamolisin-B

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

 

Names
MEROPS Namekumamolisin-B
Other namesJ-4 serine-carboxyl proteinase (Bacillus coagulans), pepstatin-insensitive acid proteinase (Bacillus), pepstatin-insensitive carboxyl proteinase (Bacillus)
MEROPS Classification
Classification Clan SB >> Subclan (none) >> Family S53 >> Subfamily (none) >> S53.005
Holotypekumamolisin-B (Bacillus coagulans) (peptidase unit: 1-362), MERNUM MER0047038
History Identifier created: MEROPS 5.3 (4 December 2000)
Activity
Catalytic typeSerine
NC-IUBMBNot yet included in IUBMB recommendations.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage patternP/Ia/Ek/FScissile bond-/R/L/- (based on 61 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 0 0 0 0 0 0 0
Pro 56 0 1 0 0 0 0 0
Ala 1 17 2 0 0 1 2 0
Val 0 0 1 0 0 1 1 0
Leu 1 1 1 0 0 1 49 0
Ile 0 32 1 0 0 0 1 0
Met 0 0 0 0 0 0 0 0
Phe 0 0 0 61 0 0 1 0
Tyr 0 0 0 0 0 0 1 0
Trp 0 0 0 0 0 0 0 0
Ser 1 2 2 0 0 1 2 0
Thr 0 1 1 0 0 0 0 0
Cys 0 0 0 0 0 0 0 0
Asn 0 1 1 0 0 1 0 0
Gln 0 1 0 0 0 0 0 0
Asp 1 2 2 0 0 1 2 0
Glu 0 1 29 0 0 1 0 0
Lys 0 1 16 0 0 1 0 0
Arg 1 2 2 0 0 53 2 0
His 0 0 1 0 0 0 0 0