Summary for peptidase T01.005: bacterial proteasome, beta component

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors

 

Names
MEROPS Namebacterial proteasome, beta component
Domain architecture
MEROPS Classification
Classification Clan PB >> Subclan PB(T) >> Family T1 >> Subfamily A >> T01.005
Holotypebacterial proteasome, beta component (Rhodococcus sp.), Uniprot accession Q53079 (peptidase unit: 66-242), MERNUM MER0001720
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Activity
Catalytic typeThreonine
PeplistIncluded in the Peplist with identifier PL00416
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.25 (Threonine-type endopeptidases) >> Peptidase 3.4.25.1
EnzymologyBRENDA database
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/-Scissile bond-/-/-/- (based on 31 cleavages)
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Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 3 0 4 1 2 2 1 2
Pro 1 1 0 0 1 1 2 2
Ala 2 1 1 1 1 2 1 2
Val 4 3 4 5 3 1 2 3
Leu 6 5 3 7 5 5 8 1
Ile 1 2 1 2 1 1 1 3
Met 3 3 2 3 1 0 0 1
Phe 1 1 1 3 0 0 0 0
Tyr 1 1 1 2 2 2 0 0
Trp 0 1 0 1 0 0 1 0
Ser 3 3 2 1 3 2 4 1
Thr 1 2 2 0 2 0 0 3
Cys 0 0 0 0 0 0 0 1
Asn 0 1 2 0 1 2 0 1
Gln 0 0 2 2 0 1 1 0
Asp 0 2 0 2 1 3 2 2
Glu 1 2 3 0 5 4 3 3
Lys 1 1 2 1 2 4 2 2
Arg 2 2 1 0 0 0 1 1
His 0 0 0 0 0 0 0 0