Summary for peptidase S10.001: carboxypeptidase Y

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors

 

Names
MEROPS Namecarboxypeptidase Y
Other namescpyA g.p. (Aspergillus nidulans), PRC1 g.p. (Saccharomyces cerevisiae), proteinase C, yeast carboxypeptidase Y
Domain architecture
MEROPS Classification
Classification Clan SC >> Subclan (none) >> Family S10 >> Subfamily (none) >> S10.001
Holotypecarboxypeptidase Y (Saccharomyces cerevisiae), Uniprot accession P00729 (peptidase unit: 112-532), MERNUM MER0002010
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Activity
Catalytic typeSerine
PeplistIncluded in the Peplist with identifier PL00372
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.16 (Serine-type carboxypeptidases) >> Peptidase 3.4.16.5
EnzymologyBRENDA database
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/AScissile bond-/-/-/- (based on 17 cleavages)
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Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 0 0 1 0 0 0 0
Pro 0 0 0 0 1 0 0 0
Ala 0 0 0 11 1 0 0 0
Val 0 0 0 1 1 0 0 0
Leu 0 0 0 1 1 0 0 0
Ile 0 0 0 1 1 0 0 0
Met 0 0 0 1 1 0 0 0
Phe 0 0 0 1 1 0 0 0
Tyr 0 0 0 0 0 0 0 0
Trp 0 0 0 0 0 0 0 0
Ser 0 0 0 0 1 0 0 0
Thr 0 0 0 0 0 0 0 0
Cys 0 0 0 0 0 0 0 0
Asn 0 0 0 0 1 0 0 0
Gln 0 0 0 0 0 0 0 0
Asp 0 0 0 0 0 0 0 0
Glu 0 0 0 0 0 0 0 0
Lys 0 0 0 0 1 0 0 0
Arg 0 0 0 0 1 0 0 0
His 0 0 0 0 0 0 0 0