Summary for inhibitor I02.015: protease nexin-2

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Inhibits Pharma

 

Names
MEROPS Nameprotease nexin-2
Other namesAlzheimer’s amyloid precursor protein Kunitz domain, amyloid precursor protein, PN2, protease nexin II
Domain architecture
MEROPS Classification
Classification Clan IB >> Subclan (none) >> Family I2 >> Subfamily (none) >> I02.015
Holotypeprotease nexin-2 (Homo sapiens), Uniprot accession P05067 (inhibitor unit: 287-345), MERNUM MER0017840
History Identifier created: MEROPS 6.1 (10 January 2003)
Human genetics
Gene symbol Locus Megabases Ensembl Entrez gene Gene Cards OMIM
APP 21q21.3 ENSG00000142192 351 APP 104760
Mouse genetics
Gene symbol Position Megabases Ensembl Entrez gene MGI
App 16:C3-qter ENSMUSG00000022892 11820 MGI:88059